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ABOUT ASI

ASI manufactures a broad range of instruments and components for High Pressure Liquid Chromatography (HPLC). While some of our products may appear rather routine at first glance, ASI instruments and components incorporate technology which is totally unique in the industry. The approach to product development at ASI has always been to “build a better mouse trap” to solve some of the most vexing problems that chromatographers face. Our solutions include: ASI Self-priming Check Valves, HyperShear Static and Dynamic Mixers, and fluid resistor based QuickSplit Fixed and Adjustable Flow Splitters. Whatever the product, the final test is customer satisfaction, so we go to great lengths to insure all ASI products work as advertised.


Steven Graham
President

We can also apply our engineering and manufacturing expertise to develop custom products to meet your specific needs. ASI has worked with, and designed OEM products for most major HPLC manufacturers. Please let us know if we can provide components or subassemblies for your next HPLC project.

Engineering Expertise

If the design is not correct to begin with, then even the best manufacturing capability in the world can do no more than produce a well made product that doesn’t work. At ASI, we apply a rigorous engineering analysis to our products before they go to the prototype stage. For our check valves, this entails stress and deflection analysis of critical components such as the seat, gaskets, and valve casing. A fluid flow analysis is then performed to make certain that the pressure drop across the valve is within proper limits. Finally, a tolerance study is performed on the design to insure that the parts fit together (it is here where 90 % of all designs fail!).
 
Once the prototype is built, we test it to verify that the performance matches the theory. Next, we build several production-like units that allow us to prove manufacturability, reliability, and most important of all, the consistency of the product performance and reliability over the specified range of manufacturing tolerances. 

Manufacturing Capabilities


Modern, State of the Art Manufacturing Facilities

Good design is the essential starting point for performance and reliability, but a good design is use-less without the manufacturing capability to execute it properly. For this reason, we have invested much time and money into our computer controlled machining centers, inspection equipment, and the experts to set up and operate this equipment properly.
Many of our products are manufactured with dimensional tolerances that are equal to 1/50 of the diameter of human hair. While these tolerances are often tighter than our designs dictate, we believe that the resulting improvement in reliability and performance is well worth the added cost in manufacturing.

Quality Control and Final Test

We believe it is not possible to manufacture reliable valves or other fluidic devices without 100% inspection of all critical parts. That is why we inspect every critical dimension on every part that affects valve performance . But even with all this inspection, we know we’re not perfect, so every mixer assembly or check valve that we ship is first subjected to a final test to prove that it performs properly under pressure.

Stephen Graham

President

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